New USP Chapter: Wetting Properties of Pharmaceutical Systems

An expert group of the US Pharmacopoeia (USP) is working on a new chapter on wetting properties of pharmaceutical systems, which may have relevance for both batch and continuous manufacturing. The draft can be found in Pharmaceutical Forum PF49(5).

The expert group proposes a standardisation of analytical technology for the characterisation of wetting properties.

The new general chapter includes the following subchapters:

• Background of wetting properties 
• Applications of wetting properties 
• Approaches to improve or modify wetting properties 
• Relevance of the surface tension of liquids for wetting properties 
• Techniques for measuring the surface tension of liquids 
• Factors influencing the surface tension of liquids 
• Evaluation of wetting properties based on the contact angle 
• Techniques for measuring the contact angle 
• Factors influencing the contact angle 
• Relevance of the surface free energy of solids 
• Techniques for measuring the surface free energy of solids

The draft of the new chapter <1243> Wetting Properties of Pharmaceutical Systems can be found Pharmaceutical Forum PF49(5). The draft is free to view, requires a free registration on the USP/NF site, though.